Thanks to the progress that have been done on the laser accelerated electron sources and taking into account the large energy range covered by it, it is now possible to envisage developments related to the medical domain. Since a few years, the community of radiobiologists, in the context of radiotherapy, are more and more excited by the encouraging results around “the flash irradiations”. By reducing the duration of the irradiation source, and for an equivalent dose, it’s possible to reduce the damage on healthy tissue while the efficiency is the same on tumoral ones.
We initiate a collaboration with radiobiologists from Institut François Jacob (CEA-Paris Saclay- Fontenay aux Roses) to explore the effect of irradiations with these new particle sources on biological cells. Our particle sources, either electrons from grating targets or electron from laser-plasma accelerator, have the specificity of being extremely short duration sources (femtosecond duration scale) associated to extrem dose.
We propose to study the effects of extrem dose rate on biological cell, with the objective to determine the dose delivered to the sample by chemical process, as it doesn’t exist at the moment for such short particle sources.
Collaboration :
- IRAMIS-LIDYL-DICO
- Institut Francois Jacob – CEA-Paris Saclay
Funding :