TUNIFOLDS : Building blocks of foldamers in the gas phase
Contacts M. Mons, V. Brenner
This topic capitalizes on the team's achievements and in particular its pioneering role in the laser spectroscopy of isolated peptides. The elementary building blocks of foldamers, based on β-peptides, i.e. peptides more complex than the natural (α-) peptides, have specific intramolecular interactions, which can be characterized by IR / UV laser spectroscopy.
This project is funded by the French National Research Agency (2017-2020, ANR-17-CE29-0008)
Ion pairs are ubiquitous in Nature, from sea water and aerosols, to living organisms. Being the very first step of crystallization of ionic species and influencing the properties of ion-concentrated solutions or ionic liquids, they also play a key role in countless applications. Although they are met in many areas of Physics, Chemistry and Biology, their characterization is complicated by the co-existence of several types of pairs and their elusive nature in solution.
In this context, this project aims at documenting net neutral ion pairs by investigating them in the gas phase using IR and UV laser spectroscopic techniques which enable us to characterize each type of ion pair individually. This experimental approach is combined with theoretical approaches aiming at identifiying the ion pairs formed in the gas phase, and extrapolating their vibrational signature in solution. Several questions are investigated by this project:
This project is funded by:
S. Habka, T. Véry, J. Donon, V. Vaquero-Vara, B. Tardivel, F. Charnay-Pouget, M. Mons, D.J. Aitken, V. Brenner, E. Gloaguen in preparation
S. Habka, "Spectroscopie optique des paires d’ions : De la caractérisation des modèles en phase gazeuse à l’identification des paires d’ions en solution", PhD thesis Université Paris-Saclay (2017)
S. Habka, V. Brenner, M. Mons, E. Gloaguen J. Phys. Chem. Lett. 7 (7) 1192 (2016)
Project acronym: FLAVE
Project title: "Project Energetics of natural turbulent flows: the impact of waves and radiation".
Researcher (PI): Basile GALLET
Host Institution (HI): CEA
Call Details: Starting Grant (StG), PE3, ERC-2017-STG
Turbulence in natural flows is an outstanding challenge with key implications for the energetics of planets, stars, oceans, and the Earth’s climate system. Such natural flows interact with waves, radiation or a combination thereof: surface waves and solar radiation on oceans and lakes, bulk waves and radiation inside the rapidly rotating and electrically conducting solar interior, etc. Standard simplified models often discard waves, radiation, or both, with dramatic consequences for the energy budget of natural flows: geostrophic models neglect waves, and Rayleigh-Bénard thermal convection considers heat diffusively injected through a solid boundary, in strong contrast with radiative heating. The purpose of the present multidisciplinary project is to develop a consistent and coupled description of natural flows interacting with waves and radiation, to properly assess their energy budget:
Start date: 2018-03-01, End date: 2023-02-28.
The ability to control chemical reactions by simultaneously monitoring in real time and under real conditions the concentration of different species is an essential tool to determine in the laboratory the reaction kinetics, in order to elucidate the associated reaction mechanisms, as well for the development and optimization of the processes on an industrial scale. Nuclear magnetic resonance (NMR) can become an effective and essential tool in this field, provided that a high quality in the measurement and detection sensitivity are obtained.
DESIR is a joint laboratory (ANR LabCom project) which brings together the strengths and skills of CortecNet and LSDRM, the research laboratory of CEA within the UMR NIMBE. The "DESIR LabCom" is based on the expertise developed by CortecNet in the synthesis of molecules enriched in stable isotopes and the expertise of LSDRM in the creation of innovative devices for the improvement of the NMR tool.
NMR is an indispensable tool for organic chemists, but its intermittent mode of use is often time consuming. The mission of the joint laboratory is to provide the community of organic chemists with an in situ NMR tracking system of their reaction synthesis. Such a device must be able to bring substantial productivity gains to chemistry laboratories for research and industry.