Exploration of inert or functionalised cubosomes by hyperpolarised xenon NMR

December 19 2024
February 3 2025
6 month
2024-exploration-of-inert-or-functionalised-cubosomes-b-en

Domain, Specialties : Physical chemistry
Keywords: Cubosomes, nanoparticles, NMR, SAXS, hyperpolarised xenon

Research Unit : NIMBE / LIONS

Summary

The internship proposed between 2 laboratories aims to use hyperpolarised Xenon NMR in organic particles formed by self-assembly of lipids. The aim is to monitor the location and accessibility of drugs or chemical functions in assemblies with different morphologies (cubic phase, sponge, etc.) in order to optimise applications in terms of delivery, transport and reactivity (catalysis).

Full description

Location

Bât. 125, CEA Saclay DRF/IRAMIS/NIMBE/LIONS et LSDRM

Internship conditions

  • Internship duration: 6 months
  • Level of study: Bac+5
  • Training: Master 2
  • Continuation in PhD thesis: No
  • Application deadline: 3 février 2025

Experimental skills

Language: English

Useful methods and technics:

  • Nanoprecipitation,
  • Formulation,
  • SAXS,
  • DLS,
  • fluorescence,
  • hyperpolarised xenon NMR,
  • 1H NMR

Supervisor

TESTARD Fabienne
Phone: 0169089642
Email :