Alexis Mifleur

  • Picture Alexis Mifleur
  • Biography

    Alexis Mifleur obtained a Master in organic chemistry in 2012 at the Université de Caen. Then he did a PhD in homogeneous catalysis at the Université de Lille / UCCS with the Professor Mathieu Sauthier on the study of the reaction of hydroalkoxylation of diene with nickel based catalyst. He obtained his diploma in 2015 and then moved to Japan for a first post-doc with Professor Mashima from Osaka University. There he worked on heterobimetallic complexes and their applications in catalysis. Alexis came back in France for a second post-doc position with Professor Pascal Fongarland in Université de Lyon / CNRS, he studied the dehydrogenation of fatty alcohols into esters from a kinetic point of view for mechanism resolution and further scale-up of the reaction. Then he joined the French Institute for Petroleum and New Energies (IFPEN) in the department of molecular catalysis, working under the supervision of Dr Lionel Magna on the thematic of ethylene oligomerization. In 2021, Alexis obtained a permanent position at the CEA in the LCMCE.


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[8] Enantioselective Nickel Catalyzed Butadiene Hydroalkoxylation with Ethanol: from Experimental Results to Kinetics Parameters. A. Mifleur, I. Suisse, A. Mortreux, M. Sauthier, Catal. Letters 2020.

[7] Online monitoring by infrared spectroscopy using multivariate analysis – background theory and application to catalytic dehydrogenative coupling of butanol to butyl butyrate. L. Violet, A. Mifleur, L. Vanoye, D. H. Nguyen, A. Favre-Réguillon, R. Philippe, R. M. Gauvin, P. Fongarland, React. Chem. Eng. 2019.

[6] Tantallacyclopentadiene as a unique metal-containing diene ligand coordinated to nickel for preparing tantalum–nickel heterobimetallic complexes. P. Laskar, K. Yamamoto, A. Srinivas, A. Mifleur, H. Nagae, H. Tsurugi, K. Mashima, Dalton Trans. 2017.

[5] Synthesis of C4 chain glyceryl ethers via nickel-catalyzed butadiene hydroalkoxylation reaction. A. Mifleur, A. Mortreux, I. Suisse, M. Sauthier, Mol. Catal. 2017.

[4] Deciphering the Mechanism of the Nickel-Catalyzed Hydroalkoxylation Reaction: A Combined Experimental and Computational Study. A. Mifleur, D. S. Mérel, A. Mortreux, I. Suisse, F. Capet, X. Trivelli, M. Sauthier, S. A. Macgregor, ACS Catal. 2017.

[3] Synthesis of Short-Chain Alkenyl Ethers from Primary and Bio-sourced Alcohols via the Nickel-Catalyzed Hydroalkoxylation Reaction of Butadiene and Derivatives. A. Mifleur, H. Ledru, A. Lopes, I. Suisse, A. Mortreux, M. Sauthier, Adv. Synth. Catal. 2016.

[2] Nickel-Catalysed Bis-Allylation of Activated Nucleophiles with Allyl-Alcohol. R. Blieck, M. S. Azizi, A. Mifleur, M. Roger, C. Persyn, M. Sauthier, H. Bonin, Eur. J. Org. Chem. 2016.

[1] Nickel-catalysed hydroalkoxylation reaction of 1,3-butadiene: ligand controlled selectivity for efficient synthesis of alkylbutenyl ethers. S. Bigot, M. S. Ibn El Alami, A. Mifleur, Y. Castanet, I. Suisse, A. Mortreux, M. Sauthier, Chem. Eur. J. 2013.