Sujet de stage / Master 2 Internship

In this project, we propose to develop grafted surfaces based on polyionenes (PI) whose structure will be optimized to fight against multi-resistant microbes. The impact of these modified surfaces on microorganisms will be studied in collaboration with a team of microbiologist from Paris-Saclay University, on a range of bacteria relevant to the medical environment. To evaluate the effect of PI on the resistance, it is necessary to conduct studies in solution that are not compatible with 2D surfaces (problem of bacteria detachment). In order to facilitate these studies, we propose to synthesize polyionene-grafted nanoparticles.