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Univ. Paris-Saclay
Protein self-assembly at interfaces: when physical chemistry meets biology
Dr. Laurent Marichal
Luxembourg Centre for Systems Biomedicine, Université du Luxembourg, Belvaux, Luxembourg
Lundi 27/11/2023, 11:00-12:01
LLB - Bât 563 p15 (Grande Salle), CEA-Saclay

Macromolecular complexes made of proteins are ubiquitous in nature. Their biological roles are plentiful and many function at interphases. Studying protein self-assembly in presence of interfaces can unravel their mechanisms of formation as well as hidden functions. Moreover, many biotechnological applications being developed nowadays rely on protein self-assembly. By using diverse examples of biological and biotechnological interests, the importance of studying protein self-assembly at interfaces will be presented. A focus will be given on amyloids (particularly functional amyloids), pharmaceutical proteins, nanovectors, and viruses. The advantages and drawbacks of some biophysical techniques relevant to the study of protein self-assembly will also be discussed.

Contact : Alain MENELLE


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