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Sujet de stage / Master 2 Internship

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Bacteriostatic polymer surfaces

Contact: CARROT Géraldine, , geraldine.carrot@cea.fr, +33 1 69 08 21 49
M1 or M2 level internship:
This project consists in the synthesis and the surface grafting of bacteriostatic polymers. The objective is to incorporate these polymers as a layer or a copolymer inside polyethylene films (main materials of food films). In addition to chemistry, both polymers and surfaces will be characterized by several analytical techniques (NMR, FTIR, XPS, microscopy, contact angles ...) before being studied in microbiology. This project will be performed at CEA ( Laboratory LICSEN/NIMBE) for the synthesis and surface chemistry part, in collaboration with INRA-AgroParisTech (Laboratory B2HM) for the characterization and microbiological tests. This project has an industrial support and may continue with a PhD thesis.

Possibility of continuation in PhD: Oui
Deadline for application:27/04/2018

Full description:
Microbial infections are a major concern for many commercial applications such as textiles, food packaging, water purification or medical equipment. Here we are interested mainly in packaging where the challenge here is to reduce the microbial loading (to increase shelf life). The objective is to preferentially incorporate bacteriostatic polymers in packaging due to their advantages of having some mobility and resistance to packaging process conditions (temperature, stretching ...). The objective of this project is to form a bacteriostatic polymer film (both attractive and biocide) where bacteria will be trapped to limit their growth and multiplication, responsible for spoilage. Promising results have already been obtained on the grafting of bacteriostatic polymers onto surfaces and we want to develop a synthetic protocol to functionalize polyethylene films, main material of food films. After characterization of polymers and surfaces that will be performed with the techniques available in Partners' Laboratories (INRA and CEA), microbiological studies (especially adhesion, viable cultivable and biofilms) will be conducted with microbiologists from INRA.
We are looking for a very motivated student with a solid background in polymer chemistry and surface science (synthesis and characterization). An interest for biology (especially microbiology) with experience in this field is desirable. Finally, the applied side of the project in the field of plastics should also be of interest for the future candidate ... This project already has a PhD funding (beginning in October 2017), following the internship.
Technics/methods used during the internship:
Polymer chemistry, FTIR, Contact angle, microscopy, profilometry, XPS

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