Personal web page : http://iramis.cea.fr/Pisp/34/lionel.poisson.html
Laboratory link : http://iramis.cea.fr/LIDYL/index.php
More : http://iramis.cea.fr/Pisp/70/eric.gloaguen.html
Flexible molecules are ubiquitous in Nature (proteins, sugars, ...) and are at the origin of many applications (drugs, molecular machines, ...). By definition, these molecules exist in several conformations that each have physical, chemical or biological properties which can vary greatly from one conformation to another. Among these properties, photoexcitation and relaxation of the electronic states are particularly sensitive to conformation: for example, the lifetime of the first excited electronic state can vary with the conformation by several orders of magnitude. However, the experimental characterisation of such conformational effects on the excited states remains rare due to the difficulty to specifically study one conformation present in a conformational mixture. This thematic is still poorly documented despite i) a need for experimental results to help the development of theoretical models, and ii) a lack of knowledge in a field where fundamental (conical intersections, ultrafast phenomena) and application (photostability, energy transfer) issues are important.
In this context, the LIDYL laboratory brings together several experimental apparatus allowing an original multi-scale (ns-fs) and conformation-resolved study of the dynamics of the electronic relaxation in flexible molecular systems. The research program will focus on biologically-relevant systems and molecular complexes, and will target:
- the observation of conformer-dependent dynamic processes and their rationalisation.
- the characterization of species previously inaccessible to conventional detection techniques.