In collaboration with chemists from ENS Lyon and from CEA/iBiTeC-S and CBM Orléans, MRI experiments on living rodents are undertaken. ¹²⁹Xe NMR-based biosensors designed to target a pulmonary disease are instilled in the lungs of the anesthetized animal. The acquisition is then performed just after the introduction of hyperpolarized xenon, which can occur many times and several tens of minutes after the biosensor instillation.